HGH Glossary

IGF-1 – Insulin Like Growth Factor

The Anti-Aging Powerhouse: IGF-1 is an anabolic growth factor molecule and has been shown in studies to be 10 times more potent than HGH in its anti-aging properties! IGF-1 can literally repair damaged DNA. This aspect of IGF-1 metabolism is rarely written about on most HGH product sales websites. The majority of the HGH “benefits” you read about are actually carried out by IGF-1 (insulin like growth factor).

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You take an HGH product for one reason, to raise IGF-1 levels.

HGH is very short lived in the blood (15-20 minutes). However, while in the blood it signals the liver to produce IGF-1.

HGH is the physiological signal that initiates the manufacture of IGF-1.

Whereas antioxidants can minimize damage to cells by countering free radical related oxidation, HGH and IGF-1 can “get under the hood” of the cells and repair damaged DNA. In this way, the aging process is directly counteracted. Conversely, if you allow HGH and IGF-1 to decline with age, cellular repair and renovation lags behind cellular damage and decay. The result is the degenerative process you and I refer to as aging.

Taking a high quality HGH supplement is way to naturally enhance the anabolic hormone IGF-1 which means you can build a stronger firmer body while combating aging and reducing body fat.

The decline of growth hormone with age is directly associated with certain aging signs like wrinkling of the skin, graying of the hair, decreased energy and sexual function, increased body fat, heart disease, weak and brittle bones, and much more.

The good news is that both HGH human growth hormone and IGF-1 can reverse these physical signs and restore energy levels, bone strength, hair color, more youthful appearing skin, and for most people reading this, an increased, youthful muscle mass simultaneously significantly reducing body fat.
Bottom Line:

Quality HGH products raise HGH levels and the primary youth-promoting anabolic hormone IGF-1. Choose your HGH product carefully.

HGH Injections

Using hgh injections (an “exogenous hormone”) is considered a direct hormonal replacement therapy. You are not supplementing or augmenting the natural cyclical production of growth hormone, you are replacing it.

Exogenous hormones come from outside the body.

Medical Note: If you decide to use injections, use only physiological doses under the supervision of a physician.

The FDA considers hgh injections a drug and therefore requires a doctor’s supervision and prescription.

Anabolic steroids, insulin, and injected human growth hormone are all examples of exogenous hormones. The main and most challenging problem with exogenous hormones stem from the fact that your body cannot control them.

All your body can do to counteract the incoming hormone is to decrease or shut-off the internal (endogenous) production of that particular hormone. These natural counter-regulatory mechanisms are called feedback loops. If there is still too much of the hormone floating around after the body shuts-off internal production, a very unhealthy situation is created.

No matter how carefully a exogenous hormone is administered, it cannot precisely mimic the subtleties of the body’s natural hormonal cycles. In the case of growth hormones–when you exceed the body’s natural hormonal levels, you can upset your entire endocrine system, with potentially serious consequences.

Dr. Daniel Rudman, in his original 1998 study, used very high doses of human growth hormone with subsequent serious side effects. In 1994 Dr. Chein and Dr. Terry lowered the doses significantly and administered them much more frequently, theoretically reducing the side effects.

More than half of Dr. Rudman’s subjects dropped out of the experiment within a year due to side effects. Carpel tunnel syndrome, fluid retention, high blood pressure, joint pain, hyperglycemia, and pancreatitis are some of the side effects associated with injected growth hormone.

Dr. Rudman was administering 16 units of human growth hormone per week! That is approximately four times the amount needed to achieve substantial improvement in the average 65 year-old.

In all fairness, most side effects happen when doses exceed the amount the body naturally produces, which in medicine, is called pharmacolgical doses.

The opposite approach is to give physiological doses, or amounts any healthy human body would normally produce for itself.

Even at physiological doses (4 units per week) there are several side effects that occasionally occur:

– edema (water retention)
– carpel tunnel syndrome
– hypertension
– increased blood glucose levels

Recent studies show that the HGH dose needed to produce optimum benefits is between 1 and 2 units each day, depending on body size. One to 1½ units daily seems to be the most effective dose, although significant benefits do occur with as little as 4 units of hgh injections weekly. Side effects are mild and transient at those doses, and diminish with continued therapy.

Studies in which significant side effects were reported used more than 2 units of hgh injections daily, and sometimes as much as 15 units daily, which is a serious overdose.

Most recent thinking is that hgh injections of one unit daily at bedtime is an effective dose with a minimal chance of side effects. This dosage is close to the same amount produced by a youthful pituitary gland. A dose of 1½ unit is also safe and increases benefit somewhat. Two units daily is recommended only for large people.

The question still remains; how does the body respond to artificial replacement of growth hormone? Because of these unanswered questions and the potential for tremendous risk, alternative HGH therapies have been vigorously investigation.

All your body can do to counteract the incoming hormone is to decrease or shut-off the internal production. If there is still too much of the hormone floating around after the body shuts-off internal production, a very unhealthy situation is created.

The scientific literature is filled with cautionary reports of potential health problems caused by using external hormones – the most troubling relating to diabetes and cancer. And while the evidence linking growth hormone replacement to the development of any specific disease is currently inconclusive, there are no studies affirming its long-term safety either.

To the contrary, based on 1) what we know about the physiological problems inherent in external hormones 2) decades of experience with estrogen, anabolic steroids, and insulin, all of which carry significant risks 3) the research developed thus far regarding the side effects and possible long-term consequences of growth hormone injections; you have to examine very closely the risk reward of hgh injections, additionally, growth hormone injections are financially costly and require shooting-up. In light of the fact that the benefits disappear when you quit the injections, you are essentially looking at an expensive lifetime drug habit, plagued with a host of undesirable side effects.

In the final analysis

Enhancing growth hormone is a terrific idea with far-reaching benefits. The key is to promote natural production of HGH, rather than rolling the dice with your health and incurring the lifetime expense of hgh injections.


HGH Sprays: The current Physician’s Desk Reference table indicates Sub-Lingual (under the tongue) oral sprays can deliver more than 92% absorption – even more than Intra-Muscular Injections, Sublingual Liquids, and Patches.

Compared to the 8-15% delivered by Capsules or 10% from Pills, the SPRAY Method is definitely superior.

Oral spray delivery systems are not really all that new either. For almost a decade, they’ve been gaining acceptance in the medical community as a preferred method for promptly delivering medications.

For instance, several states have already passed legislation that requires all self-administered heart medicine to be packaged in spray form for optimal rapid absorption.

HGH Sprays article.


“Homeopathic hgh is a natural remedy that is reported to have no side effects.” Robert Mendelsohn, M.D., Professor, University of Illinois Medical School and best-selling author.

Homeopathy Explained

Conventional medicine cures using chemical pharmaceuticals to attack symptoms – for example – an aspirin for a headache – an antihistamine for runny nose.

Homeopathic hgh, is intended to work by acting as a catalyst to signal the body at the cellular level.


HGH in the form of pills and powders generally use amino acids and are called “secretagogues,” they stimulate the pituitary gland to increase HGH production. Other proprietary agents (nutrients) are usually part of the pills and powders mix and give each product a presumed advantage.

Studies show certain amino acids, such as and L-arginine, can stimulate pituitary HGH.

Secretagogue formulations may utilize several different compounds:

– Amino acids
– Nutrients
– Herbs

Secretagogues are designed to create specific metabolic pathways which work in tandem to prompt a pulse release of HGH from the pituitary gland, while simultaneously inhibiting those compounds which block HGH.

Using compounds together in formula form appear to raise HGH levels. Oral supplementation of these key compounds appears to release HGH by working with muscle physiology, neutralizing other glandular signals which inhibit the release of HGH, enhancing protein response to build muscle, boosting cell replication and fat breakdown, stimulating certain sex hormones which build muscle and enhance stamina and energy, and by targeting specific brain chemicals which are involved in HGH actions.

Most contain large amounts of amino acids, particularly L-Arginine.

As indicated above, resistance to the secretagogue compounds and nutrients develops over time. This is called tachyphylaxsis and is the reason athletes cycle (alternate days on, days off) these types of supplementation.

Cycling gives the body (receptor sites) time to rest.

Many of the secretagogue pills and powders have carriers and buffers to help absorption, assimilation and facilitate transport of the amino acids to the brain.

– Carriers – generally complex glucose peptides which supposedly protect the amino acids from the gastrointestinal acids and helps absorption.
– Buffers – the stomach is a pretty harsh environment – buffers are used to buffer the stomach acids and further shield the amino acids from being destroyed.