HGH research is based on levels of circulating IGF-1 blood serum levels.
IGF-1 blood serum levels are the true bio-markers of HGH production in the body. The following chart indicates the range of IGF-1 blood serum levels for different age groups.
| Information Source |
Assays for Establishing Levels of Circulating HGH |
|||||||
|---|---|---|---|---|---|---|---|---|
| Grow Young with HGH |
IGF-1
(Somatomedin-C) Levels |
|||||||
| Human age in years |
0.2-5 |
6-8 |
9-11 |
12-15 |
16-24 |
25-39 |
40-54 |
>55 |
| Mean values of IGF-1 in ng/ml |
17-248 |
88-474 |
110-565 |
202-957 |
182-780 |
114-492 |
90-360 |
71-290 |
History and HGH Research
Prior to the advent of recombinant DNA technology, the only source of growth hormone was from human cadavers. More than 27,000 children worldwide were treated with growth hormone of this source (pit-hGH).
Due to short supply, children were treated with low doses and interrupted schedules. As a result, their response and ultimate height was mitigated. Distribution of pit-hGH was stopped in the United States and most of Europe in 1985, with the emergence of Creutzfeldt-Jakob Disease.
This is a rare and fatal spongiform encephalopathy, caused by a small pathogen called a prion. This is the same pathogen that causes “Mad Cow Disease” recently seen in Europe from infected cattle.
It is impossible to catch Creutzfeldt-Jakob Disease or any other infection from recombinant human growth hormone because it is not derived from a human or animal source, but from a purified tissue culture. For purposes of this article, the term growth hormone, GH or hGH will mean growth hormone made by recombinant DNA technology.
In a paper published by the Journal of American Geriatrics Society in 1985, endocrinologist the late Daniel Rudman from Madison, Wisconsin first proposed that the safe new form of HGH could be used to reverse aging in HGH-deficient individuals.
Since then, numerous HGH studies have been conducted. By repeatedly having passed controlled, randomized, double-blind studies, HGH has been proven to prevent or reverse aging’s effects.
Food Sources
HGH research has shown that production of HGH in the body can be stimulated by oral administration of HGH precursor Growth Hormone Releasing Agents (GHRA) and IGF-1 simulators: combinations of the amino acids arginine (2-5 g daily) , ornithine (2-5 g), lysine (1-2 g), and glutamine (2 g).
These amino acids, when taken in the correct combination, preferably on an empty stomach and just before bedtime, are reported to produce a significant increase in the circulating HGH. In addition, 2 g daily gamma-aminobutyric acid (GABA), an amino acid essential for proper brain function, has been shown to increase the HGH in circulation.
All these supplements should be cycled to allow natural production of HGH to continue, but cycling recommendations (as well as suggested daily dosages) vary considerably within the community of scientists and nutrition experts.
Antiaging Considerations Based on HGH Research
In 21-year-olds, the normal levels of circulating HGH is approximately 10 milligrams per deciliter of blood; in 61-year-olds, the average is 2 ml/dl, which represents an 80 percent decrease.
In some cases, older people have circulatory HGH levels that are less than 10 percent of youthful levels. By age 65, an estimated 50 percent of the population is partially or wholly HGH deficient. By the time men and women are in their 70s, 38 percent of adults are as deficient in HGH as growth-stunted children.
Based on hgh research studies results indicate that increased circulatory HGH has greater capacity to prevent and reverse the aging process than any other substance known to science.
The goal of all forms of HGH replacement therapy is to restore normal levels to those of early adulthood, for example, to age 30 years. HGH replacement improves sex drive, sexual performance, fertility, sperm production, and ovulation.
Side note: HGH research has shown that HGH therapy is more effective when administered in conjunction with DHEA therapy, as well as estrogen/progesterone replacement for women and testosterone replacement for men.
Dr. Edmund Chein’s Study
One of the most prominent figures in anti-aging and hgh research today is Dr. Edmund Chein, medical director of the Palm Springs Life Extension Institute. In 1994, he became the first doctor in the US to openly offer replacement therapy.
To date, he has treated over 800 people over the age of 40 with low dose, high frequency treatments. Significantly, 20% of Dr. Chein’s patients are physicians themselves who understand the benefits of this therapy. Most notably, Dr. Chein has successfully reversed his own heart disease with this remediation.
Dr. Chein claims a 100% success rate for his brand of therapy. He guarantees the following results: a gain in bone density of 1.5%-2.5% every six months; a decrease in body fat of 10%-12% every six months; and a gain in muscle mass of 8%-10% every six months. These changes continue until a patient’s body composition mimics that of a 20 year old.
