Overall IGF-1 (insulin like growth hormone) function, also known as somatomedin is dependent on the production and presence of HGH (human growth hormone).
While in the bloodstream HGH signals the liver to produce IGF-1. IGF-1 is ten times more potent than HGH, and is directly responsible for almost all of the ultimate benefits of HGH you read about.
What is IGF-1?
IGF-1 is a growth factor similar to insulin in molecular structure; IGF-1 consists of 70 amino acids in a single chain. The production of IGF-1 stimulates systemic body growth, and promotes growth in almost every cell of the body. IGF-1 impacts cellular growth and maintenance in skeletal muscle, skin, bone, cartilage, kidney, nerves, and the lungs.
IGF-1 is essential for maintaining the communication and cooperation between nerve and muscular cells, and further, for muscular strength and recovery from both nerve and muscular cell injury, by assisting in cell maintenance, and enhancing cell specialization.
IGF-1 is produced throughout life, with the lowest levels occurring in infancy and older age and the highest production during the pubertal growth period. It is now known that effective signaling through the insulin/IGF-1 receptor pathway is one of the most significant factors in the biological aging process.
IGF-1 levels change
When a human is 30 years old, the body produces approximately 10 milligrams of IGF-1 per day. After 30 years of age, the levels of HGH and IGF-1 produced daily declines, significantly.
Research clearly establishes the impacts of IGF-1 deficiency in humans in the form of general aging.
Factors that are known to reduce levels of HGH and IGF-1 include:
- Poor nutrition
- High body mass index
- Reduced estrogen
- Lower exercise levels
- ;Higher stress levels
IGF-1 is critical for enabling the body to continue to move cells from the “resting” phase to the “growth” and “repair” phase. During the aging process as cellular growth is reduced, normalizing IGF-1 levels assists in bringing the aging, slower cells back into a performance state, where cell activity is again optimized.
Studies show the importance of IGF-1 in gaining control over the aging process and since HGH is directly responsible for the signaling and production of the IGF-1 hormone a high quality HGH supplement is recommended to insure the proper IGF-1 biofeedback mechanisms are in place.