Understanding HGH Growth Hormone

HGH is produced in the front part of the pituitary gland, which is located near the base of the brain. Production and release of HGH is largely governed by a number of feedback systems, the most important part of which involves a part of the brain called the hypothalamus. In a stripped down version of how the pituitary and the hypothalamus affect each other, we can regard the hypothalamus as a governor to the pituitary.

When levels of HGH in the blood become altered, this is detected by the hypothalamus, which reacts to the change. For example, if levels of HGH have reached what is regarded as maximal by the hypothalamus, the hypothalamus releases a hormone called somatostatin, which tells the pituitary to cut back on the amount of HGH is is releasing. Somatostatin is also known as Growth Hormone Inhibiting Factor (GHIH), and it is released from the pancreas, thyroid and gut as well.

When levels of circulating HGH are low, this too is detected by the hympothalumus, which releases another hormone called Growth Hormone Releasing Hormone (GHRH), which in turn instructs the pituitary to release more HGH.

Since GHRH pulses regularly over the 24 hour period it is known that GHIH is the true “gatekeeper” for HGH release. GHIH will occasionally drop to low levels and this will allow surges of HGH production before feedback shuts off the production again.

HGH supplements generally do not supply molecular HGH but instead, supply amino acids and homeopathic formulations that have been designed to impact the actions of 24 hours pulse cycle of GHRH. Higher quality products demonstrate a more consistent ability to positively influence 24 hours pulse cycle of GHRH.

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